Simmons-Smith Reaction Mechanism

Simmon Smith reaction is most powerful organic cheletropic (reaction) method for cyclopropane preparation from diiodomethane (CH2I2) in the presence of zinc-copper couple (Zn-Cu) from unfunctionalized alkenes (e.g., cyclohexene, styrene) stereospecifically.

Acetoacetic-Ester Condensation (Claisen Condensation)

claisen condensation class 12

Formation of aceto-acetic-ester by the reaction of sodium ethoxide with ethyl acetate is called Claisen Condensation reaction or The Claisen Condensation reaction between Esters (containing α-hydrogens), in the presence of Bases such as sodium ethoxide, gives β-ketoesters via stabilized anion of the β-keto Ester.

Favorskii Rearrangement

Favorskii-rearrangement

What is Favorskii Rearrangement explain? Favorskii Rearrangement is organic reaction of α-halo ketones (chlorine, bromine, or iodine) having at least one α-hydrogen, with a nucleophile (alcohol, amine, or H2O) in the presence base (usually an alkoxide or hydroxide) give carboxylic acids or carboxylic acid derivatives via a cyclopropanone intermediate. It is widely used organic reaction … Read more