Pummerer Rearrangement: Mechanism, Applications Examples

Pummerer Rearrangement

Formation of α-substituted sulfides from the corresponding sulfoxides (must have at least one hydrogen atom at their α-position) is referred to as the Pummerer rearrangement.

Schmidt Reaction (Rearrangement): definition| Mechanism| example

Schmidt Reaction for Synthesis of Nitrile and Amide

Schmidt reaction is a acid-catalyzed Rearrangement reaction of hydrazoic acid reactions of electrophiles, like carbonyl compounds, alkenes tertiary and alcohols. The following these substrates include amines, nitriles, amides or imines, rearrangement and extrusion of nitrogen.

Favorskii Rearrangement


What is Favorskii Rearrangement explain? Favorskii Rearrangement is organic reaction of α-halo ketones (chlorine, bromine, or iodine) having at least one α-hydrogen, with a nucleophile (alcohol, amine, or H2O) in the presence base (usually an alkoxide or hydroxide) give carboxylic acids or carboxylic acid derivatives via a cyclopropanone intermediate. It is widely used organic reaction … Read more