The Henry Reaction

henry-reaction, Nitro-Aldol condensation

  The Henry reaction was first reported by Belgian chemist Louis Henry in 1895. The Henry reaction involves the addition of a nitronate salt to a carbonyl compound, usually an aldehyde. The reaction is also referred to as a Nitroaldol reaction. It is C-C bond-forming reaction used in organic synthesis.   Mechanism:   The Henry Reaction Mechanism can present in two steps … Read more

Alder Ene Reaction

The Alder Ene reaction, also known as the Alder-ene reaction or the ene reaction, is a type of pericyclic reaction in organic chemistry. It involves the addition of a π-bond (ene) to an unsaturated double bond (eneophile) in the presence of a Lewis acid or a transition metal catalyst. The reaction proceeds through a concerted … Read more

Aza-Claisen Rearrangement:

The Aza-Claisen rearrangement is a chemical reaction involving a nitrogen atom’s migration from one position to another within a molecule. It is named after the Claisen rearrangement, a well-known rearrangement reaction involving oxygen atoms. The mechanism of the aza-Claisen rearrangement: The mechanism of the aza-Claisen rearrangement involves three steps:  Protonation: The reaction often starts with … Read more

Mannich Reaction : Definition, Mechanism, Application, Explanation

mannich reaction

Mannich Reaction PDF | Mannich Reaction Examples | Mannich Reaction Definition | Mannich Reaction Mechanism PDF | Mannich Reaction PPT | Mannich Reaction Procedure The Mannich Reaction was invented in 1912 by German chemist Carl Mannich, and has been the subject of study, extensions, and applications ever since. Definition: The condensation of a CH-activated compound … Read more

Vilsmeier–Haack formylation

The formylation of electron-rich aromatic compounds with a mixture of dimethylformamide and phosphorus oxychloride POCl3 is commonly referred to as the Vilsmeier reaction, or sometimes the Vilsmeier-Haack reaction, from the names of the two German chemists who first described it in 1927.