Smiles Rearrangement Reaction : Mechanism , Application and Modification
Hello, here is the Smiles Rearrangement Reaction type of nucleophilic aromatic substitution with mechanism, examples, and modification.
Name Reaction
The Stevens Rearrangement:
Stevens rearrangement is a base-promoted [1,2]-migration rearrangement of quaternary ammonium salts or sulfonium salts to the corresponding tertiary amines or sulfides. Stevens rearrangement involves the [1,2]-migration of one of the groups on the nitrogen or sulfur atom.
Stetter Reaction: synthesis of 1 4-diketones and γ-oxo nitriles
The addition of aliphatic or aromatic aldehydes across activated double bonds in the presence of a nucleophilic catalyst for the synthesis of 1,4-diketones and γ-oxo nitriles is known as the Stetter reaction.
Suzuki cross-coupling Reaction: Examples | Mechanism | Application|
Suzuki cross -coupling reaction is an coupling reaction and also known as Suzuki-Miyaura cross-coupling, its coupling between a boronic acid and an organohalide or aromatic halides by using Palladium (0) complex is used to catalyst and base.
Aldol Reaction: Condition | Mechanism | Examples
Definitionn: The Aldol reaction is a versatile carbon-carbon bond-forming reaction in organic chemistry. It involves the condensation of an enol or enolate (derived from a carbonyl compound) with another carbonyl compound, forming a β-hydroxy carbonyl compound, known as an aldol product. The reaction takes its name from the combination of “aldehyde” and “alcohol,” as the … Read more
Alder Ene Reaction
The Alder Ene reaction, also known as the Alder-ene reaction or the ene reaction, is a type of pericyclic reaction in organic chemistry. It involves the addition of a π-bond (ene) to an unsaturated double bond (eneophile) in the presence of a Lewis acid or a transition metal catalyst. The reaction proceeds through a concerted … Read more