Smiles Rearrangement Reaction : Mechanism , Application and Modification
Hello, here is the Smiles Rearrangement Reaction type of nucleophilic aromatic substitution with mechanism, examples, and modification.
Name Reaction
The Stevens Rearrangement:
Stevens rearrangement is a base-promoted [1,2]-migration rearrangement of quaternary ammonium salts or sulfonium salts to the corresponding tertiary amines or sulfides. Stevens rearrangement involves the [1,2]-migration of one of the groups on the nitrogen or sulfur atom.
Stetter Reaction: synthesis of 1 4-diketones and γ-oxo nitriles
The addition of aliphatic or aromatic aldehydes across activated double bonds in the presence of a nucleophilic catalyst for the synthesis of 1,4-diketones and γ-oxo nitriles is known as the Stetter reaction.
Suzuki cross-coupling Reaction: Examples | Mechanism | Application|
Suzuki cross -coupling reaction is an coupling reaction and also known as Suzuki-Miyaura cross-coupling, its coupling between a boronic acid and an organohalide or aromatic halides by using Palladium (0) complex is used to catalyst and base.
Schmidt Reaction (Rearrangement): definition| Mechanism| example
Schmidt reaction is a acid-catalyzed Rearrangement reaction of hydrazoic acid reactions of electrophiles, like carbonyl compounds, alkenes tertiary and alcohols. The following these substrates include amines, nitriles, amides or imines, rearrangement and extrusion of nitrogen.
Sandmeyer Reaction: Definition| Mechanism| Example| Application
The Sandmeyer reaction is an organic substitution type reaction used for the synthesis of aryl halide from an aryl diazonium salt. the catalyst used in Sandmeyer reaction is a copper(I) halide like chloride, bromide or iodide ions catalyst. significantly, The reaction include trifluoromethylation, hydroxylation, cyanation, and halogenation type reaction on benzene.