Smiles Rearrangement Reaction : Mechanism , Application and Modification
Hello, here is the Smiles Rearrangement Reaction type of nucleophilic aromatic substitution with mechanism, examples, and modification.
Name Reaction
The Stevens Rearrangement:
Stevens rearrangement is a base-promoted [1,2]-migration rearrangement of quaternary ammonium salts or sulfonium salts to the corresponding tertiary amines or sulfides. Stevens rearrangement involves the [1,2]-migration of one of the groups on the nitrogen or sulfur atom.
Aza-[2,3]-Wittig Rearrangement: Mechanism | Examples
The rearrangements reactions are important Name reaction in organic chemistry. Wittig rearrangement, first reported by G. Wittig and L. Löhmann in 1942, The Wittig rearrangement converts α-metalated ethers to metal alkoxides, yielding secondary or tertiary alcohols. Its nitrogen analog, the aza-Wittig rearrangement, transforms α-metalated tertiary amines into rearranged metal amides, producing homoallylic secondary amines. This … Read more
Carroll Rearrangement: Mechanism | Examples
The Carroll Rearrangement is a named reaction in organic chemistry, where the [3,3]-sigmatropic rearrangement of allylic β-keto esters to form γ,δ-unsaturated ketones is called the Carroll rearrangement. It is also known as the Kimel–Cope or decarboxylative Claisen rearrangement. Here, we will explore the Carroll rearrangement and its mechanism, accompanied by some interesting examples. Carroll Rearrangement … Read more
Cannizzaro Reaction: Mechanism | Examples
Cannizzaro Reaction is a base-catalyzed redox reaction in which aromatic aldehydes, formaldehyde, or other aliphatic aldehydes lacking α-hydrogen are converted into the corresponding alcohols and carboxylic acids. Cannizzaro reaction is a named reaction in organic chemistry. Here, we will explore the Cannizzaro Reaction and its mechanism, accompanied by some interesting examples. Cannizzaro Reaction Mechanism: Several … Read more
Stetter Reaction: synthesis of 1 4-diketones and γ-oxo nitriles
The addition of aliphatic or aromatic aldehydes across activated double bonds in the presence of a nucleophilic catalyst for the synthesis of 1,4-diketones and γ-oxo nitriles is known as the Stetter reaction.