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stetter-reaction

Stetter Reaction: synthesis of 1 4-diketones and γ-oxo nitriles

September 17, 2025 by Chemistry Guide
The Stetter reaction

The addition of aliphatic or aromatic aldehydes across activated double bonds in the presence of a nucleophilic catalyst for the synthesis of 1,4-diketones and γ-oxo nitriles is known as the Stetter reaction.

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