Aza-Cope Rearrangement : Mechanism| Examples | Application

Aza-cope rearrangement definition: The N-substituted 1,5-dienes isomerize via a [3,3]-sigmatropic rearrangement after heating called as the Aza-Coperearrangement. In this blog we are explained 2-Aza-Cope Rearrangement, 3-Aza-Cope Rearrangement, Aza-Cope Rearrangement, Aza-Cope Rearrangement Mechanism, Aza-Cope Rearrangement Examples

1-Aza-Cope Rearrangement

Aza-Cope Rearrangement : Mechanism| Examples | Application are here

2-Aza-Cope Rearrangement:

The rearrangement of cis-2-vinylcyclopropyl isocyanates to 1-azacyclohepta-4,6-dien-2-ones is known as 2-aza-rearrangement

3-Aza-Cope Rearrangement:

The 3-aza-Cope rearrangement is also known as the aza-Claisen rearrangement.

Aza-Cope Rearrangement Mechanism:

Aza-Cope Rearrangement Mechanism shows these to steps : The aza-Cope rearrangement is a concerted process, and it usually takes place via a chair like transition state where the substituents are arranged in a quasi-equatorial position. The mechanism of aza-Cope rearrangement is a concerted process and takes place via a chair-like transition state where the substituents are arranged in a quasi-equatorial position.

Aza-Cope Rearrangement Examples with Mechanism:

Aza-Cope Rearrangement Examples with Mechanism

Aza-Cope Rearrangement Applications:

synthesis of cis-hexahydroisoquinolinone is prominent applications of aza-cope rearrangement

Related Reactions:

1. Cope rearrangement
2. Mannich Reaction
3. Aza-Cope Rearrangement : Mechanism| Examples | Application

References:

1. aza-cope-rearrangement- sciencedirect^^