Reimer-Tiemann Reaction : Mechanism, Application, Examples
The Reimer-Tiemann reaction is an organic transformation that converts a phenol into an 2-hydroxy benzaldehyde using chloroform, a base, and an acid work-up at last step. Reimer-Tiemann Reaction Mechanism: The reaction commences with removing a proton from chloroform by the base, forming a trichlorocarbanion. This intermediate, however, spontaneously eliminates a chloride ion, generating a neutral … Read more